Methods in Medical Research

of which 19 are included in the volume under review. This volume contains an excellent introductory chapter by the editors and thorough discussions of the following topics: Physical Chemistry and Chemical Kinetics of Enzymes (E. A. MoelwynHughes) Enzyme Specificity (B. Helferich) Enzymes in Relation to Genes, Viruses, Hormones, Vitamins, and Chemotherapeutic Drug Action (M. G. Sevag, J. S. Gots, and E. Steers) Cytochemical Foundations of Enzyme Chemistry (A. L. Dounce) Modern Aspects of Enzymatic Adaptation (S. Spiegelman) Enzyme Inhibition (L. Massart) Enzymes and Immunology (J. R. Marrack) Enzymes Hydrolyzing Fats and Esters (R. Ammon and M. Jaarma) Acetylcholine Esterase and Choline Esterase (K. Augustinsson) Phosphatases (J. Roche) Metaphosphate and its Enzymatic Breakdown (B. Ingelman) Sulfatases (C. Fromageot) Invertase (C. Neuberg and I. Mandl) alpha-4-Glucosidases (A. Gottschalk) beta-Glucosidase (S. Veibel) Hydrolysis of Galactosides, Mannosides and Thioglycosides (S. Veibel) beta-Gluruconidase (W. H. Fishman) Amylases and the Hydrolysis of Starch and Glycogen (K. Myrbiick and G. Neumuller) The appearance of the succeeding parts of this encyclopedic treatise will provide enzyme chemists with a reference work of inestimable value. The editors and publishers are to be commended for their courage in embarking on this impressive enterprise.